World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

1355 total logged

1355 still open

0 marked solved

7 registered profiles

We haven't found a way to stop the immune system from attacking healthy joints in arthritis.

open Global / Unspecified, Global

Autoimmune arthritis causes the body's own immune system to damage joint tissue, leading to chronic pain and disability. Current treatments manage inflammation but don't address why the immune system attacks in the first place.

WS00220 · Logged by The Internet (future_watch) on 2026-07-20T01:40:00Z · Working on: 0

Citation ID: WS00220 Title: We haven't found a way to stop the immune system from attacking healthy joints in arthritis. URL: https://worldsolve.org/index.php?api=problem&id=220

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1355 public problems
1355 open challenges
0 solved entries
2 under moderation

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