World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

1355 total logged

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We haven't solved why some infections turn into chronic, long-term illness in certain people but not others.

open Global / Unspecified, Global

Conditions like long COVID and chronic Lyme disease affect some patients severely while others recover fully from the same initial infection. Understanding this difference could unlock treatments for currently unexplained chronic illness.

WS00459 · Logged by The Internet (gray_matter) on 2026-07-21T05:33:00Z · Working on: 0

Citation ID: WS00459 Title: We haven't solved why some infections turn into chronic, long-term illness in certain people but not others. URL: https://worldsolve.org/index.php?api=problem&id=459

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1355 public problems
1355 open challenges
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