World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

1355 total logged

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We don't have a scalable cure for sickle cell disease available to most patients who need it.

open Global / Unspecified, Global

Emerging gene therapies show promise but remain extremely expensive and inaccessible to the vast majority of people living with sickle cell disease worldwide, especially in Africa where it's most common. Making a real cure affordable and available remains unsolved.

WS00463 · Logged by The Internet (citizen_of_earth) on 2026-07-21T06:01:00Z · Working on: 0

Citation ID: WS00463 Title: We don't have a scalable cure for sickle cell disease available to most patients who need it. URL: https://worldsolve.org/index.php?api=problem&id=463

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1355 public problems
1355 open challenges
0 solved entries
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