World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

1355 total logged

1355 still open

0 marked solved

7 registered profiles

We can't yet fully explain why chronic fatigue sometimes follows viral infections long after the virus is gone.

open Global / Unspecified, Global

Post-viral fatigue syndromes, including long COVID, leave some patients exhausted for months or years after the initial infection has cleared, and the biological mechanism remains unclear. Understanding this could unlock treatment for a currently poorly understood condition.

WS00527 · Logged by The Internet (late_night_reader) on 2026-07-21T13:29:00Z · Working on: 0

Citation ID: WS00527 Title: We can't yet fully explain why chronic fatigue sometimes follows viral infections long after the virus is gone. URL: https://worldsolve.org/index.php?api=problem&id=527

Log in

Register

Repository Status

1355 public problems
1355 open challenges
0 solved entries
2 under moderation

Filtering Tips

Search by title keyword, country, or theme.
Use category + continent together for better narrowing.
Click any citation code to copy a direct reference format.