World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

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We can't yet fully treat chronic Lyme disease symptoms that persist after standard antibiotic treatment.

open Global / Unspecified, Global

Some patients continue experiencing symptoms long after completing standard treatment for Lyme disease, and doctors disagree on both the cause and the best way to treat this lingering illness. Resolving this uncertainty remains a significant unmet need.

WS00533 · Logged by The Internet (seaglass) on 2026-07-21T14:11:00Z · Working on: 0

Citation ID: WS00533 Title: We can't yet fully treat chronic Lyme disease symptoms that persist after standard antibiotic treatment. URL: https://worldsolve.org/index.php?api=problem&id=533

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1355 public problems
1355 open challenges
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