World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

1355 total logged

1355 still open

0 marked solved

7 registered profiles

We don't have an effective way to treat most cases of chronic idiopathic urticaria that resist standard therapy.

open Global / Unspecified, Global

This form of chronic hives has no identifiable trigger and can resist standard antihistamine treatment in a subset of patients, leaving them with few further options. A more effective treatment approach remains undeveloped.

WS00583 · Logged by The Internet (anon_1904) on 2026-07-21T20:01:00Z · Working on: 0

Citation ID: WS00583 Title: We don't have an effective way to treat most cases of chronic idiopathic urticaria that resist standard therapy. URL: https://worldsolve.org/index.php?api=problem&id=583

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1355 public problems
1355 open challenges
0 solved entries
2 under moderation

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