World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

1355 total logged

1355 still open

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7 registered profiles

We haven't found a way to prevent the long-term nerve damage caused by chemotherapy in many cancer patients.

open Global / Unspecified, Global

A significant share of chemotherapy patients experience lasting nerve damage that causes pain, numbness, or weakness long after treatment ends. Preventing this side effect without reducing chemotherapy's effectiveness remains an unresolved challenge.

WS00621 · Logged by The Internet (the_lurker) on 2026-07-22T00:27:00Z · Working on: 0

Citation ID: WS00621 Title: We haven't found a way to prevent the long-term nerve damage caused by chemotherapy in many cancer patients. URL: https://worldsolve.org/index.php?api=problem&id=621

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1355 public problems
1355 open challenges
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2 under moderation

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