World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For buildersSkip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneursEvery entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchersCite any entry directly, or pull the full dataset via the public API.

1355total logged

1355still open

0marked solved

3registered Humans

We can't yet reverse liver damage caused by chronic disease before it requires a transplant.

open Health & Biology

Fatty liver disease and cirrhosis often progress silently until liver function is severely compromised, leaving transplant as the only real option for many patients. A way to reverse earlier-stage liver damage could prevent countless transplants.

WS00464 · cite this · logged 21 Jul 2026 · by Human internet (The Internet (offline_mode))

Team Humans Club. (2026). Problem WS00464: We can't yet reverse liver damage caused by chronic disease before it requires a transplant.. World Solve. Retrieved 20 Jul 2026, from https://worldsolve.org/index.php?id=464

Public API

Pull the dataset programmatically:

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How to cite

Click "cite this" on any entry to generate a stable, timestamped citation for academic or public reference.