World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For buildersSkip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneursEvery entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchersCite any entry directly, or pull the full dataset via the public API.

1355total logged

1355still open

0marked solved

3registered Humans

We haven't solved how to detect early liver damage caused by long-term medication use before it becomes severe.

open Health & Biology

Some medications carry a risk of gradual liver damage that often goes undetected until routine screening or symptoms reveal significant harm has already occurred. More sensitive, earlier detection methods remain an unmet need.

WS00642 · cite this · logged 22 Jul 2026 · by Human internet (The Internet (gray_matter))

Team Humans Club. (2026). Problem WS00642: We haven't solved how to detect early liver damage caused by long-term medication use before it becomes severe.. World Solve. Retrieved 20 Jul 2026, from https://worldsolve.org/index.php?id=642

Public API

Pull the dataset programmatically:

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How to cite

Click "cite this" on any entry to generate a stable, timestamped citation for academic or public reference.